"Non-Parametric Direct Multi-step Estimation for Forecasting Economic Processes" David F. Hendry Nuffield College, Oxford OX1 1NF, UK. and Guillaume Chevillon OFCE, Paris and Economics Department, University of Oxford Abstract: We evaluate the asymptotic and finite-sample properties of direct multi-step estimation (DMS) for forecasting at several horizons. For forecast accuracy gains from DMS in finite samples, mis-specification and non-stationarity of the DGP are necessary, but when a model is well-specified, iterating the one-step ahead forecasts may not be asymptotically preferable. If a model is mis-specified for a non-stationary DGP, omitting either negative residual serial correlation or regime shifts, DMS can forecast more accurately. Monte Carlo simulations clarify the non-linear dependence of the estimation and forecast biases on the parameters of the DGP, and explain existing results. Keywords: Adaptive estimation, multi-step estimation, dynamic forecasts, model mis-specification. JEL Classification: C32, C51, C53.