Nontokozo is a human rights-based and feminist practising social epidemiologist. Her research focuses on the epidemiology of sexual violence perpetrated by intimate partners and/or non-partners among adolescent boys and girls, which includes adolescent mothers. She uses prospective cohort and population-based cross-sectional data to identify interventions that can accelerate the reduction of sexual violence in Africa. She is currently a DPhil candidate in the Department of Social Policy and Intervention, with a working title 'Disrupting compounding challenges of gender, sexual violence and HIV among adolescents living in South Africa: Ensuring no one is Left Behind'.

Nontokozo has served as a panel expert on sexual and reproductive health and rights for adolescents, addressing policymakers at the South African Development Community (SADC) regional meetings and African Union meetings. Her collaborative work with UNICEF Eastern and Southern Africa includes multiple policy briefs on drivers and mitigators of adolescent HIV risk, including the negative impact of violence on ART adherence.

Within academia, Nontokozo is a vocal advocate for enacting equality, diversity, and inclusion practices. At the University of Cape Town, she was chair of the department’s Transformation Committee and served as an Employment Equity representative. At Nuffield College, she is a member of the Equality, Diversity and Inclusion committee.

Nontokozo received her Master's in Public Health from the University of Cape Town. She holds a Bachelor of Science degree in Chemistry from York University, Canada.